Diethylpropion, Bupropion, and Psychoses
نویسندگان
چکیده
منابع مشابه
GABA and acute psychoses.
Recent attempts to explain acute psychotic behaviour in terms of disordered cerebral neurotransmitter function have largely concerned the monoamines, serotonin, dopamine and noradrenaline (Crow, 1978). Most prominent among these endeavours is the dopamine hypothesis of schizophrenia, which in its current form proposes that the 'positive' symptoms of acute schizophrenia (or Schneider first-rank ...
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Bupropion is a widely used antidepressant, smoking cessation aid, and weight-loss therapy. It is administered as a racemic mixture, but the pharmacokinetics and activity of bupropion are stereoselective. The activity and side effects of bupropion are attributed to bupropion and its metabolites S,S- and R,R-OH-bupropion, threohydrobupropion, and erythrohydrobupropion. Yet the stereoselective met...
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DIETHYLPROPION ("Tenuate") has been shown to be useful in the treatment of refractory obesity (Seaton et al., 1961). Appetite suppression with the standard preparation is reported to last about four hours (Spielman, 1959) and the drug must be taken at least three times daily. This paper reports the use of a longacting preparation of the drug, which need be taken only once a day. It is marketed ...
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In March 2010, Orexigen(R) Therapeutics submitted a new drug application (NDA) for approval of naltrexone sustained release (SR)/bupropion SR (Contrave(R)) for the treatment of obesity in the US. The tablet contains naltrexone SR 32 mg and bupropion SR 360 mg. The drug has been tested in four randomized, double-blind, placebo-controlled, phase III trials and the co-primary endpoints were met in...
متن کاملPrader-Willi syndrome and psychoses.
Prader-Willi syndrome (PWS) is associated with an insatiable appetite and (often) other maladaptive behaviours (self-injury, sleep disorders, insistence on routines, and temper tantrums). Psychoses are not a recognised feature. Most affected people have a chromosome 15 abnormality (deletion, disomy, structural rearrangement, etc.). Three people with PWS who developed psychotic disorders in earl...
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ژورنال
عنوان ژورنال: British Journal of Psychiatry
سال: 1988
ISSN: 0007-1250,1472-1465
DOI: 10.1192/bjp.153.2.265